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Wegovy (Semaglutide) – Weight Management Medication**

Overview:
Wegovy (semaglutide) is an FDA-approved prescription medication designed to aid chronic weight management in adults with obesity or overweight individuals with at least one weight-related condition (e.g., type 2 diabetes, high blood pressure). It belongs to the GLP-1 receptor agonist class and works by regulating appetite and food intake.

Key Features:
Active Ingredient: Semaglutide (same as Ozempic, but at a higher dose for weight loss).
Administration: Once-weekly subcutaneous injection.
FDA Approval: Approved for long-term weight management.
Efficacy: Clinical trials show significant weight loss (average 12-15% of body weight over 68 weeks with diet and exercise).

Who Can Use Wegovy?
– Adults with a BMI ≥30 (obesity).
– Adults with a BMI ≥27 (overweight) + weight-related conditions (e.g., hypertension, dyslipidemia).
– Not recommended for those with a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2).

How It Works:
– Mimics the GLP-1 hormone to increase insulin secretion, slow gastric emptying, and reduce hunger signals in the brain.

Potential Side Effects:
– Common: Nausea, diarrhea, vomiting, constipation, abdominal pain.
– Serious (rare): Pancreatitis, gallbladder issues, kidney problems, hypoglycemia (if used with other diabetes meds).

Dosage & Administration:
– Starts at a low dose (0.25 mg/week) with gradual increases to 2.4 mg/week to minimize side effects.

Lifestyle Considerations:
– Should be combined with a reduced-calorie diet and increased physical activity for optimal results.

Prescription Requirements:
– Available only by prescription; not covered by all insurance plans (prior authorization may be required).

Alternatives:
– Other GLP-1 agonists (e.g., Saxenda/liraglutide, Zepbound/tirzepatide).
– Non-GLP-1 weight loss medications (e.g., phentermine, Contrave).

Latest Research & News:
– Updates on Wegovy’s cardiovascular benefits (e.g., reduced risk of heart attack/stroke in certain patients)